https://theboutroslab.r-universe.devRecent package updates in theboutroslabR-universehttps://github.com/theboutroslab.pnghttps://theboutroslab.r-universe.devWed, 18 Mar 2026 22:27:01 GMTpboutros@sbpdiscovery.org (Paul C. Boutros)Genomic regions processing using open-source command line tools such as 'BEDTools', 'BEDOPS' and 'Tabix'. These tools offer scalable and efficient utilities to perform genome arithmetic e.g indexing, formatting and merging. bedr API enhances access to these tools as well as offers additional utilities for genomic regions processing.https://github.com/r-universe/theboutroslab/actions/runs/25986346331Wed, 18 Mar 2026 22:27:01 GMTbedr1.1.5successhttps://theboutroslab.r-universe.devhttps://github.com/theboutroslab/package-bedrUsing-bedr.RmdUsing-bedr.html2015-08-06 13:14:582025-04-04 22:46:55pboutros@sbpdiscovery.org (Paul C. Boutros)Kataegis is a localized hypermutation occurring when a region is enriched in somatic SNVs. Kataegis can result from multiple cytosine deaminations catalyzed by the AID/APOBEC family of proteins. This package contains functions to detect kataegis from SNVs in BED format. This package reports two scores per kataegic event, a hypermutation score and an APOBEC mediated kataegic score. Yousif, F. et al.; The Origins and Consequences of Localized and Global Somatic Hypermutation; Biorxiv 2018 <doi:10.1101/287839>.https://github.com/r-universe/theboutroslab/actions/runs/25986385869Wed, 18 Mar 2026 22:17:16 GMTSeqKat0.0.9successhttps://theboutroslab.r-universe.devhttps://github.com/theboutroslab/package-seqkatvignette.Rmdvignette.htmlSeqKat2017-05-31 19:35:582018-01-09 22:25:45